|
Symbol Name ID |
Cit
citron MGI:105313 |
| Darker colors indicate more annotations |
| Human Phenotypes | Primary microcephaly |
Spasticity |
Hypoplasia of the brainstem |
Ventriculomegaly |
Microlissencephaly |
Simplified gyral pattern |
Agenesis of corpus callosum |
Hypoplasia of the corpus callosum |
Cerebellar hypoplasia |
Delayed speech and language development |
Delayed early-childhood social milestone development |
Intellectual disability |
Hyperreflexia |
Global developmental delay |
Delayed fine motor development |
Delayed gross motor development |
Seizure |
| Disease(s) Associated with CIT | |||||||||||||||||
| primary autosomal recessive microcephaly 17 |
| Mouse Phenotypes | increased susceptibility to pharmacologically induced seizures |
myoclonus |
increased neuron apoptosis |
decreased brain weight |
decreased midbrain size |
abnormal diencephalon morphology |
abnormal hippocampus morphology |
abnormal dentate gyrus morphology |
abnormal cerebral hemisphere morphology |
abnormal olfactory bulb morphology |
small olfactory bulb |
abnormal cerebellum morphology |
abnormal cerebellar Purkinje cell layer |
thin cerebellar granule layer |
abnormal cerebellum lobule morphology |
small cerebellum |
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| Availability | Mouse Genotype | ||||||||||||||||
| Cittm1Fdc/Cittm1Fdc | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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